I start melons, squash, and some tomatoes from seed every year- I love to try different varieties than the same standards the nurseries usually carry.   In recent years there has been alot more selection for tomatoes and peppers which is nice, hopefully they expand other vegetable selections as well.   Some new things I'm growing this year include 'Moon & Stars' watermelon, 'Pomodoro' tomato, 'Napoli' zucchini,  'Crystal Apple' cucumbers, 'Haogen' melon, 'Banana' melon, 'African Horned' melon, and 'French pickling' cucumbers.